Selected Publications (2007-2010) (For all publications please click here)

- van Spronsen M and Hoogenraad CC (2010) Synapse pathology in psychiatric and neurological disease Curr Neurol Neurosci Rep In Press

- Schlager MA, Kapitein LC, Grigoriev I, Burzynski GM, Wulf PS, Keijzer N, de Graaff E, Fukuda M, Shepherd IT, Akhmanova A and Hoogenraad CC (2010) Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D related protein-1 (BICDR-1) regulates neuritogenesis. EMBO J In Press

- Splinter D, Tanenbaum ME, Lindqvist A, Jaarsma D, Flotho A, Yu KL, Grigoriev I, Engelsma D, Haasdijk ED, Keijzer N, Demmers J, Fornerod M, Melchior F, Hoogenraad CC, Medema RH and Akhmanova A (2010). Bicaudal D2, dynein and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry. PLoS Biol, In Press

- Kapitein LC, Schlager MA, Kuijpers M, Wulf PS, van Spronsen M, MacKintosh FC, Hoogenraad CC (2010). Mixed microtubules steer dynein-driven cargo transport into dendrites. Current Biol 20(4):290-299

- Hoogenraad CC, Popa I, Futai K, Sanchez-Martinez E, Wulf PS, van Vlijmen T, Dortland BR, Oorschot V, Govers R, Monti M, Heck AJ, Sheng M, Klumperman J, Rehmann H, Jaarsma D, Kapitein LC, van der Sluijs P (2010). Neuron specific Rab4 effector GRASP-1 coordinates membrane specialization and maturation of recycling endosomes. PLoS Biol. 8(1):e1000283

- Stiess M, Maghelli N, Kapitein LC, Gomis-Rüth S, Wilsch-Bräuninger M, Hoogenraad CC, Tolic Nørrelykke IM, Bradke F. (2010) Axon extension occurs independently of centrosomal microtubule nucleation. Science. 327(5966):704-7

- Hoogenraad CC, Bradke F (2009) Control of neuronal polarity and plasticity--a renaissance for microtubules? Trends Cell Biol. 19(12):669-76.

- Schlager MA, Hoogenraad CC (2009) Basic mechanisms for recognition and transport of synaptic cargos. Mol Brain. 4;2(1):25.

- van Woerden GM, Hoebeek FE, Gao Z, Nagaraja RY, Hoogenraad CC, Kushner SA, Hansel C, De Zeeuw CI, Elgersma Y (2009) betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nat Neurosci. 12(7):823-5.

- Martin S, Henley JM, Holman D, Zhou M, Wiegert O, van Spronsen M, Joëls M, Hoogenraad CC, Krugers HJ (2009).Corticosterone alters AMPAR mobility and facilitates bidirectional synaptic plasticity. PLoS One. 2009;4(3):e4714.

- Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, Honnappa S, Buey RM, Hoogenraad CC, Dogterom M, Borisy GG, Steinmetz MO, Akhmanova A (2009) Mammalian end binding proteins control persistent microtubule growth. J Cell Biol. 184(5):691-706

- Jaworski J, Kapitein LC, Gouveia SM, Dortland BR, Wulf PS, Grigoriev I, Camera P, Spangler SA, Di Stefano P, Demmers J, Krugers H, Defilippi P, Akhmanova A, Hoogenraad CC (2009). Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity. Neuron 61(1):85-100.

- Kapitein LC, Janson ME, van den Wildenberg SM, Hoogenraad CC, Schmidt CF, Peterman EJ (2008). Microtubule-driven multimerization recruits ase1p onto overlapping microtubules. Curr Biol. 18(21):1713-7

- Teuling E, van Dis V, Wulf PS, Haasdijk ED, Akhmanova A, Hoogenraad CC, Jaarsma D (2008). A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice. Hum Mol Genet 17(18):2849-62

- Jaarsma D, Teuling E, Haasdijk ED, De Zeeuw CI, Hoogenraad CC (2008). Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice. J Neurosci 28(9):2075-88

- Grigoriev I, Gouveia SM, van der Vaart B, Demmers J, Smyth JT, Honnappa S, Splinter D, Steinmetz MO, Putney JW Jr, Hoogenraad CC, Akhmanova A (2008). STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER. Curr Biol 12;18(3):177-82.

- Jaworski J, Hoogenraad CC, Akhmanova A (2008) Microtubule plus-end tracking proteins in differentiated mammalian cells. Int J Biochem Cell Bio. 40(4):619-37.

- Teuling E, Ahmed S, Haasdijk E, Demmers J, Steinmetz MO, Akhmanova A, Jaarsma D, Hoogenraad CC (2008). Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates. J Neurosci. 27(36):9801-15

- Grigoriev I, Splinter D, Keijzer N, Wulf PS, Demmers J, Ohtsuka T, Modesti M, Maly IV, Grosveld F, Hoogenraad CC, Akhmanova A (2007) .Rab6 regulates transport and targeting of exocytotic carriers. Dev Cell 13(2):305-14.

- Hoogenraad CC, Feliu-Mojer MI, Spangler SA, Milstein AD, Dunah AW, Hung AY, Sheng M (2007), Liprin-alpha1 degradation by calcium/calmodulin-dependent protein kinase II regulates LAR receptor tyrosine phosphatase distribution and dendrite development. Dev Cell. 12(4):587-602.

- Erez H, Malkinson G, Prager-Khoutorsky M, De Zeeuw CI, Hoogenraad CC, Spira ME (2007). Formation of microtubule-based traps controls the sorting and concentration of vesicles to restricted sites of regenerating neurons after axotomy. J Cell Biol. 176(4):497-507

- Sheng M, Hoogenraad CC (2007). The postsynaptic architecture of excitatory synapses: a more quantitative view. Annu Rev Biochem. 76:823-47